Chemical Feature-Based Molecular Modeling of Urotensin-II Receptor Antagonists: Generation of Predictive Pharmacophore Model for Early Drug Discovery

Table 2

Statistical values and features for the top 10 hypotheses.

Hypotheses	Total cost	Cost difference (null-total cost)	RMSD	Correlation	Features
1	150.914	39.69	0.88645	0.902269	HBA_L, HY, 2RA
2	157.651	32.953	1.10718	0.840131	HBA_L, HY, 2RA
3	173.856	16.748	1.42113	0.727559	HBA_L, HY, 2RA
4	174.987	15.617	1.48308	0.688064	HBA_L, HY, 2RA
5	176.221	14.383	1.46284	0.7101	HBA_L, HY, 2RA
6	179.14	11.464	1.56714	0.640751	HBA_L, HY, 2RA
7	180.984	9.62	1.60018	0.620886	HBA_L, HY, 2RA
8	181.365	9.239	1.6061	0.617387	HBA_L, HY, 2RA
9	182.587	8.017	1.62925	0.602328	HBA_L, HY, 2RA
10	183.831	6.773	1.64821	0.590495	HBA_L, HY, 2RA