Research Article
Design, Synthesis, and In Vitro Antiplatelet Aggregation Activities of Ferulic Acid Derivatives
Table 1
Effects of target compounds on the platelet aggregations induced by adenosine diphosphate (ADP) in vitro.
| | Compd. | IC50 (M) | Compd. | IC50 (M) | Compd. | IC50 (M) |
| | Aspirin | 90.0 | 6g | >200 | 7g | 79.9 | | FA | 66.3 | 6h | >200 | 7h | 35.8 | | 6a | 80.2 | 7a | 87.4 | 8a | >200 | | 6b | >200 | 7b | 44.7 | 8b | >200 | | 6c | 93.0 | 7c | 107.4 | 8c | 82.2 | | 6d | 81.3 | 7d | >200 | 9a | >200 | | 6e | >200 | 7e | 43.1 | 9b | >200 | | 6f | >200 | 7f | 27.6 | 9c | 64.3 |
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