In Vitro Enzyme Inhibition Potentials and Antioxidant Activity of Synthetic Flavone Derivatives
Table 3
DPPH radical scavenging activity of flavone derivatives.
% Scavenging activity (DPPH)
25 μg/mL
50 μg/mL
75 μg/mL
100 μg/mL
125 μg/mL
150 μg/mL
Ascorbic acid
65.23 ± 0.41
71.56 ± 0.61
75.26 ± 0.68
81.09 ± 0.42
86.11 ± 0.87
90.68 ± 0.58
Tocopherol
72.32 ± 0.36
79.16 ± 0.57
84.41 ± 0.61
90.18 ± 0.53
92.24 ± 0.75
94.33 ± 0.49
Rutin
79.03 ± 0.76
83.11 ± 0.43
87.63 ± 0.81
91.25 ± 0.61
95.35 ± 0.66
97.67 ± 0.51
F1
32.12 ± 0.61
38.46 ± 1.17
46.48 ± 0.57
55.81 ± 0.81
61.65 ± 1.06
63.44 ± 0.75
F2
16.65 ± 1.04
21.62 ± 0.67
30.94 ± 0.63
37.63 ± 0.39
44.74 ± 0.86
47.76 ± 0.82
F3
42.47 ± 0.84
51.62 ± 1.21
59.74 ± 0.75
63.18 ± 0.54
68.21 ± 0.61
70.16 ± 0.69
F4
35.31 ± 0.92
38.32 ± 0.62
55.27 ± 0.43
61.65 ± 0.49
65.36 ± 0.72
68.14 ± 0.55
F5
41.96 ± 0.54
53.78 ± 1.31
61.21 ± 0.69
65.23 ± 0.71
71.96 ± 0.47
73.12 ± 0.48
All the values were expressed as mean ± SEM. , , and when compared to control group (one-way ANOVA followed by Dunnett's: compare all versus control test).
