In Vitro Enzyme Inhibition Potentials and Antioxidant Activity of Synthetic Flavone Derivatives
Table 4
Hydrogen peroxide radical scavenging activity of flavone derivatives.
% Scavenging activity (H2O2)
25 μg/mL
50 μg/mL
75 μg/mL
100 μg/mL
125 μg/mL
150 μg/mL
Ascorbic acid
71.23 ± 0.65
76.57 ± 0.49
84.06 ± 0.81
88.19 ± 0.56
92.21 ± 0.71
96.63 ± 0.63
Tocopherol
73.02 ± 0.43
76.26 ± 0.66
82.43 ± 0.73
90.38 ± 0.87
93.65 ± 0.63
95.47 ± 0.48
Rutin
77.13 ± 0.69
82.15 ± 0.87
88.43 ± 0.34
92.35 ± 0.61
97.16 ± 0.46
98.84 ± 0.74
F1
28.21 ± 0.84
32.52 ± 0.77
38.33 ± 0.87
47.41 ± 0.36
55.34 ± 0.67
57.84 ± 0.69
F2
13.75 ± 0.60
17.12 ± 0.97
25.77 ± 0.68
32.35 ± 0.79
36.47 ± 0.68
42.19 ± 0.48
F3
37.43 ± 0.48
48.35 ± 0.91
53.19 ± 0.57
56.78 ± 0.45
60.46 ± 0.46
63.16 ± 0.84
F4
31.62 ± 0.54
35.13 ± 0.77
46.91 ± 0.74
51.85 ± 0.78
57.74 ± 0.56
61.39 ± 0.43
F5
43.07 ± 0.48
51.72 ± 0.76
57.68 ± 0.49
62.86 ± 0.65
70.21 ± 0.71
72.26 ± 0.78
All the values were expressed as mean ± SEM. , , and when compared to control group (one-way ANOVA followed by Dunnett’s: compare all versus control test).