Amidine Sulfonamides and Benzene Sulfonamides: Synthesis and Their Biological Evaluation

Table 1

Physiochemical and analytical data of sulfonamides.

Compounds	Molecular weight	Elemental analysis (found/cal.) %
		C	H	N	S	p
3a	271.29	44.33/44.27	4.85/4.83	15.42/15.49	11.83/11.82	10.8
3b	285.32	46.35/46.30	5.39/5.31	14.68/14.73	11.29/11.24	10.8
4a	411.45	46.77/46.71	4.15/4.16	10.26/10.21	15.65/15.59	4.7
4b	439.51	49.17/49.19	4.89/4.82	9.58/9.56	14.57/14.59	4.7
6a	425.48	47.96/47.99	4.54/4.50	7.88/7.98	15.12/15.07	4.7
9a	234.28	56.33/56.39	4.28/4.30	11.88/11.96	13.61/13.69	8.5
9b	248.30	58.03/58.05	4.81/4.87	11.22/11.28	12.85/12.91	8.5
10a	374.44	54.50/54.53	3.68/3.77	7.51/7.48	17.15/17.13	5.3
10b	402.49	56.73/56.70	4.52/4.51	6.88/6.96	15.86/15.93	5.3
12a	388.46	55.63/55.65	4.11/4.15	7.16/7.21	16.46/16.51	5.3
15a	243.28	49.43/49.37	5.41/5.39	5.73/5.76	13.16/13.18	5.0
15b	257.31	51.33/51.35	5.81/5.88	5.36/5.44	12.49/12.46	4.8

p values from ACD, Inc.