Journal of Chemistry / 2015 / Article / Tab 2

Research Article

Amidine Sulfonamides and Benzene Sulfonamides: Synthesis and Their Biological Evaluation

Table 2

Zone of inhibition and MIC of sulfonamides against pathogenic bacterial strains.

Compounds Name of bacteria
Gram (+) bacterial strainsGram (−) bacterial strains
S. aureusB. subtilisE. coli
(ATCC 25923)(ATCC 6633)(ATCC 25922)
Zone of inhibitionMICZone of inhibitionMICZone of inhibitionMIC

3a—, —, ——, —, —9, —, —>160
3b32, 29, 26408, —, —>160—, —, —
4a—, —, ——, —, ——, —, —
4b—, —, ——, —, —28, 25, 2280
6a—, —, ——, —, —9, —, —>160
9a—, —, —9, —, —1609, —, —>160
9b—, —, —8, —, —>160—, —, —
10a9, —, —>160—, —, —14, 10, —160
10b27, 24, 2280—, —, ——, —, —
12a9, —, —>16028, 24, 2180—, —, —
15a29, 26, 2180—, —, ——, —, —
15b—, —, —27, 24, 228028, 25, 2080
Ciprofloxacin36, 34, 310.536, 33, 310.535, 34, 310.5
Sulfamethoxazole—, —, —16, 13, —16033, 28, 2540

Zone of inhibition was measured in mm at concentration of 160, 80, and 40 μg mL−1.
MIC (minimum inhibitory concentrations) were measured in μg mL−1.
Control drug; sulfa drug.

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