Review Article

Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review

Table 1

PLGA membranes in animal and human studies.

Type of PLGA membranesClinical applicationSpeciesStudy

PGA/PLA membrane + deproteinized bovine boneGuided bone regeneration of bony defectsHumans[25]
PGA/PLA membranesPeriodontology
(class II furcation)
Humans[26]
PGA/PLA membranes + hydroxyapatitePeriodontology
(class II furcation)
Humans[26]
PLGA membranesBony defects distal to mandibular second molarsHumans[17]
PLGA membranesGuided bone regeneration around dental implantsHumans[27]
PLGA membranesBone regenerationDogs[16]
PLGA membrane + atelocollagen gel + rhBMP-2
(recombinant human bone morphogenetic protein-2)
Mandibular transsectionsRabbits[20]
PLGA membrane + atelocollagen gel + rhBMP-2
(recombinant human bone morphogenetic protein-2)
Mandibular defectsRabbits[21]
PLGA-grafted hyaluronic acid bilayer filmsGuided bone regenerationRats[22]
Polylactic acid-co-glycolic acid-co--caprolactone membraneBone healingDogs[23]
PLGA membranesBone healingRabbits[18]
PLGA/SiO2 PLGA/TiO2 membranes Bone healingRabbits[24]