Study on Molecular Recognition between Euphorbia Factor L713283 and β-Tubulin via Molecular Simulation Methods

Figure 4

The docking result of L713283 with β-tubulin. (a) The docked conformations were clustered with the RMSD cutoff value of 0.2 nm. (b) The binding modes of both L713283 docked conformations and the crystal structure of Taxol ligand. Taxol ligand is represented using ball-and-stick model in red. The representative docked conformations of L713283 are shown with stick model in green, blue, orange, and purple, respectively.

(a)

(b)