An Unprecedented Straightforward Synthesis of Chiral Pyrrolo[3,4-<i>b</i>]quinolone and Pyrrolo[3,2-<i>b</i>]quinolone Backbones Starting from<i> trans</i>-4-Hydroxy-L-proline

<div>Proposed mechanism for the Friedländer reaction leading to<b> 5</b> and<b> 6</b>.</div>

Journal of Chemistry

sch4

Scheme 4

Scheme 4: An Unprecedented Straightforward Synthesis of Chiral Pyrrolo[3,4-<i>b</i>]quinolone and Pyrrolo[3,2-<i>b</i>]quinolone Backbones Starting from<i> trans</i>-4-Hydroxy-L-proline 

Scheme 4 | An Unprecedented Straightforward Synthesis of Chiral Pyrrolo[3,4-b]quinolone and Pyrrolo[3,2-b]quinolone Backbones Starting from trans-4-Hydroxy-L-proline 