Core Cross-linked Star Polymers for Temperature/pH Controlled Delivery of 5-Fluorouracil

Figure 7

Release of 5-fluorouracil from different star polymers at constant temperatures: free 5-fluorouracil in PBS at pH 6 at 37°C (○) and at pH 7.4 at 37°C (■) and at 42°C (□); star polymer [poly(NIPAAm-co-4MBA)-b-polyHA]₁-EGDMA₁₀ in PBS at pH 6 at 37°C (●) and at pH 7.4 at 37°C (▼) and at 42°C (▽); star polymer [polyNIPAAm-b-polyHA]₁-EGDMA₁₀ in PBS at pH 7.4 at 37°C (▲) and 42°C (∆).