Core Cross-linked Star Polymers for Temperature/pH Controlled Delivery of 5-Fluorouracil

Table 3

Reactions for preparation of star polymers with a random number of arms and a cross-linked poly(EGDMA) core.

Entries	Star polymer; cross-linker : macro-CTA : I]	Crosslinker : macro-CTA : I	(GPC); (g/mol)	Ð; ()	Yield (wt%)
1	[PolyNIPAAm-b-polyHA]-EGDMA	20 : 1 : 0.2	41,740	1.333	70
2	[PolyNIPAAm-b-polyHA]-EGDMA	10 : 1 : 0.2	136,500	1.200	77
3	[(Poly(NIPAAm-co-4MBA9%)-b-polyHA)]-EGDMA	20 : 1 : 0.2	76,600	1.175	65
4	[(Poly(NIPAAm-co-4MBA5%)-b-polyHA)]-EGDMA	10 : 1 : 0.2	100,700	1.290	70

Cross-linker: EGDMA; macro-CTA: block copolymer as macro chain transfer agent; I: initiator. Macro-CTA of = 12,780 g/mol. Macro-CTA of = 32,070 g/mol. Macro-CTA of = 21,730 g/mol. Macro-CTA of = 28,570 g/mol.