Determination of Cefoperazone Sodium in Presence of Related Impurities by Improved Classical Least Squares Chemometric Methods: A Comparative Study

Table 1

Four-level three-factor experimental design of the training set (16 mixtures) and test set (9 mixtures) shown as concentrations of the mixture components in g mL⁻¹.

Training set			Test set
CEF	7-ACA	5-MER	CEF	7-ACA	5-MER
18	0.13	0.065	25	0.17	0.09
18	0.15	0.07	19	0.14	0.07
20	0.15	0.09	22	0.18	0.075
20	0.2	0.07	21	0.14	0.08
26	0.15	0.065	23	0.15	0.065
20	0.13	0.085	25	0.2	0.085
18	0.18	0.085	19	0.13	0.08
24	0.18	0.07	22	0.16	0.07
24	0.15	0.085	21	0.16	0.08
20	0.18	0.065
24	0.13	0.09
18	0.2	0.09
26	0.2	0.085
26	0.18	0.09
24	0.2	0.065
26	0.13	0.07