Determination of Cefoperazone Sodium in Presence of Related Impurities by Improved Classical Least Squares Chemometric Methods: A Comparative Study

Table 2

Analysis results for the prediction of training set (autoprediction) of CEF by the proposed chemometric models.

Training set	⁢CLS		⁢SRACLS		⁢NAP-CLS		⁢OSC-CLS		⁢DOSC-CLS
Taken (μg mL^−1)	Found (μg mL^−1)	%	Found (μg mL^−1)	%	Found (μg mL^−1)	%	Found (μg mL^−1)	%	Found (μg mL^−1)	%
18	18.78	104.33	18.29	101.61	18.55	103.06	18.58	103.22	18.58	103.22
18	17.86	99.21	17.99	99.94	17.99	99.94	18.01	100.06	18.01	100.06
20	19.7	98.52	19.85	99.25	19.88	99.40	19.84	99.20	19.84	99.20
20	19.69	98.45	19.77	98.85	19.84	99.20	19.89	99.45	19.88	99.40
26	25.72	98.94	26.17	100.65	26.21	100.81	26.14	100.54	26.14	100.54
20	19.78	98.91	19.92	99.60	19.90	99.50	19.89	99.45	19.89	99.45
18	17.85	99.19	17.94	99.67	17.89	99.39	17.88	99.33	17.88	99.33
24	23.57	98.21	23.84	99.33	23.82	99.25	23.74	98.92	23.74	98.92
24	23.93	99.71	24.16	100.67	24.09	100.38	24.00	100.00	24.01	100.04
20	19.74	98.72	19.81	99.05	19.72	98.60	19.72	98.60	19.72	98.60
24	24.03	100.11	24.14	100.58	24.10	100.42	24.01	100.04	24.01	100.04
18	18.35	101.97	18.16	100.89	18.08	100.44	18.07	100.39	18.07	100.39
26	26.37	101.44	26.45	101.73	26.37	101.42	26.25	100.96	26.25	100.96
26	26.1	100.39	25.19	96.88	25.91	99.65	25.93	99.73	25.93	99.73
24	24.33	101.36	24.26	101.08	23.93	99.71	24.13	100.54	24.13	100.54
26	26.18	100.69	26.04	100.15	25.73	98.96	25.94	99.77	25.94	99.77
Mean		100.01		99.99		100.10		100.01		100.01
SD		1.64		1.21		1.07		1.06		1.07
RMSEC		0.32		0.28		0.22		0.20		0.20