Synthesis, Characterization, and Anticancer Activity of New Benzofuran Substituted Chalcones

Table 1

Evaluation of the cytotoxicity and values (µM) of chalcone compounds and docetaxel (reference chemotherapeutic drug) of two cancer cell lines. is the concentration of drug that reduces cell growth by 50%.

Compound	MCF-7	PC-3
	(µM)	(µM)
D1	2.12	1.54
3a	1.89	1.67
3b	1.45	1.24
3c	5.01	6.31
3d	5.79	1.81
3e	0.42	0.67
3f	2.30	2.47
3g	4.43	6.11
3h	2.55	2.57
3i	6.28	6.30
3j	−0.21	0.92
Docetaxel (reference drug)	−0.48	−0.52