Research Article
Synthesis and Biological Evaluation of New (−)-Gossypol-Derived Schiff Bases and Hydrazones
Table 2
Antibacterial activity of compounds against human pathogenic bacteria.
| | Number | Compounds | MIC (µg/ml) | | Staphylococcus aureus (ATCC 6538) | Bacillus cereus (ATCC 21768) | Bacillus subtilis (ATCC 6633) | Escherichia coli (ATCC 25931) | Pseudomonas aeruginosa (ATCC 9027) |
| | (1) | 4a | — | — | — | — | — | | (2) | 4b | — | — | — | — | — | | (3) | 4c | — | — | — | — | — | | (4) | 4d | — | — | — | — | — | | (5) | 8a | 1024 | 1024 | | — | — | | (6) | 8b | 1024 | — | 1024 | — | — | | (7) | 8c | — | — | — | — | — | | (8) | 8d | — | — | — | — | — | | (9) | 8e | 1024 | — | — | — | — | | (10) | 12a | — | — | — | — | — | | (11) | 12b | — | — | — | — | — | | (12) | 12c | — | — | — | — | — | | (13) | 12d | — | — | — | — | — | | (14) | 12e | — | — | — | — | — | | (15) | Streptomycin sulfate | 20 | 20 | 5 | 20 | 20 | | (16) | (−)-Gossypol | 15 | 15 | 16 | Nd | Nd |
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Not determined.
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