Research Article

A Novel and Chemoselective Process of N-Alkylation of Aromatic Nitrogen Compounds Using Quaternary Ammonium Salts as Starting Material

Table 2

Chemoselective alkylation of nitrogen heterocyclic rings with tetradecyltrimethylammonium bromide.

ā€‰Starting materialProductTime (h)Yield (%)
R = CH3

11b373
22b478
33b576
44b597
55b1874
66b546
77b373
1111b643

Yields refer to chromatographically pure isolated compounds.