Synthesis of Ibuprofen Conjugated Molecular Transporter Capable of Enhanced Brain Penetration

<div>(a) HPLC chromatogram of biotin (internal standard) and (<b>8</b>) in plasma after 3 h incubation time; retention time of biotin and plasma: 3.38 min, ibuprofen: 3.96 min, and (<b>8</b>): 6.40 min and (b) the remained percentage of (<b>8</b>) in plasma over incubation time.</div>

Journal of Chemistry

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Figure 4

Figure 4: Synthesis of Ibuprofen Conjugated Molecular Transporter Capable of Enhanced Brain Penetration 