Research Article
A Stability-Indicating RP-HPLC-UV Method for Determination and Chemical Hydrolysis Study of a Novel Naproxen Prodrug
Table 6
Robustness analysis.
| Parameter | Peak areas | pH | Wavelength |
| Normal (pH 4.0, 272 nm detection) | 576794 | 576794 |
| Change 1 (pH 3.7, 270 nm detection) | 597818 | 588379 | 596622 | 585239 | 598154 | 602703 |
| Change 2 (pH 4.3, 274 nm detection) | 599370 | 577334 | 598128 | 573709 | 596365 | 576894 |
| % RSD | 1.342097 | 1.738497 |
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