Research Article

A Stability-Indicating RP-HPLC-UV Method for Determination and Chemical Hydrolysis Study of a Novel Naproxen Prodrug

Table 6

Robustness analysis.

ParameterPeak areas
pHWavelength

Normal (pH 4.0, 272 nm detection)576794576794

Change 1 (pH 3.7, 270 nm detection)597818588379
596622585239
598154602703

Change 2 (pH 4.3, 274 nm detection)599370577334
598128573709
596365576894

% RSD1.3420971.738497