Research Article
Synthesis and Pharmacological Activities of Pyrano[2,3-d]pyrimidine and Pyrano[2,3-d]pyrimidine-5-one Derivatives as New Fused Heterocyclic Systems
Table 1
The antioxidant activities of the synthesized compounds.
| Compound number | Antioxidant activity | Bleomycin dependent DNA damage | Absorbance | Inhibition % |
| 1 | 0.111 | 78.6 | 0.098 | 2 | 0.427 | 17.9 | 0.127 | 3 | 0.419 | 19.4 | 0.135 | 4 | 0.062 | 88.1 | 0.083 | 5 | 0.393 | 24.4 | 0.138 | 7a | 0.083 | 84.0 | 0.091 | 7b | 0.428 | 17.7 | 0.151 | 8 | 0.274 | 47.3 | 0.089 | 9 | 0.446 | 14.2 | 0.142 | 10 | 0.060 | 88.5 | 0.066 | 11 | 0.355 | 31.7 | 0.112 | Ascorbic acid | 0.065 | 89.2 | 0.076 | ABTS | 0.520 | ā | ā |
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