Research Article

Preparation and Optimization of 10-Hydroxycamptothecin Nanocolloidal Particles Using Antisolvent Method Combined with High Pressure Homogenization

Table 5

Preparation of HCPTNPs with poloxamer 188 by HPH.

Pressure (bar)Mass (mg)MPS (nm)ZP (mV)

6000.5272.6
2.5181.9
8000.5214.1
2.5147.3
10000.5144.3
2.5273.6