Research Article
Xanthone and Flavone Derivatives as Dual Agents with Acetylcholinesterase Inhibition and Antioxidant Activity as Potential Anti-Alzheimer Agents
Scheme 2
Reagents and conditions for the synthesis of carbaldehyde xanthone 5 and aminated xanthones 6–9 and 11-12. (a) (1) HMTA/AcOH, reflux, 3 h, (2) 15% HCl, reflux, 30 min; (b) amine (2.4 eq), NaBH (OAc)3 (4 eq), AcOH (2 eq), MeOH, room temperature, overnight.