Xanthone and Flavone Derivatives as Dual Agents with Acetylcholinesterase Inhibition and Antioxidant Activity as Potential Anti-Alzheimer Agents

Table 2

Iron chelating activity of tested compounds.

Compounds	% of chelation at 100 µM	IC50 (µM)
1		n.d.
2	n.a.	n.d.
3
6	n.a.	n.d.
7	n.a.	n.d.
8	n.a.	n.d.
9	n.a.	n.d.
11	n.a.	n.d.
12	n.a.	n.d.
13		n.d.
14

Results are given as mean ± SEM of three independent experiments performed in triplicate; n.a.: not active; n.d.: not determined. EDTA (positive control): IC₅₀: 30.66 ± 0.17 . ; .