Research Article

Xanthone and Flavone Derivatives as Dual Agents with Acetylcholinesterase Inhibition and Antioxidant Activity as Potential Anti-Alzheimer Agents

Table 3

AChE inhibitory activity of tested compounds.

Compounds% of inhibition at 100 µMIC50 (µM)

1n.a.n.d.
2n.d.
3
6n.d.
7n.d.
8n.d.
9n.d.
11n.a.n.d.
12n.a.n.d.
13n.a.n.d.
14

Results are given as mean ± SEM of three independent experiments performed in triplicate; n.a.: not active; n.d.: not determined. Galantamine (positive control): IC50: 6.59 ± 0.15 . ; .