Research Article
Synthesis and Experimental Validation of New Designed Heterocyclic Compounds with Antiproliferative Activity versus Breast Cancer Cell Lines MCF-7 and MDA-MB-231
Scheme 1
Reagents and conditions: (a) ClCH2COC6H4R, EtOH, reflux; (b) PPA, room temperature or H2SO4 conc., 140°C.