Research Article

CryoProtect: A Web Server for Classifying Antifreeze Proteins from Nonantifreeze Proteins

Table 4

Performance comparisons among various types of machine learning algorithms and protein sequence as evaluated on 10-fold CV and external validation tests.

Classifier Feature(s) 10-fold CV setExternal validation set
Ac (%) Sn (%) Sp (%) MCC YI Ac (%) Sn (%) Sp (%) MCC YI

RFAAC
DPC
AAC + DPC

DTAAC
DPC
AAC + DPC