CryoProtect: A Web Server for Classifying Antifreeze Proteins from Nonantifreeze Proteins

Table 5

Performance comparisons of CryoProtect with the existing methods on the external validation set(s).

Method	Ac (%)	Sn (%)	Sp (%)	MCC	YI
iAFP	95.30	13.26	97.09	0.086	0.10
AFP-Pred	77.34	91.16	77.04	0.23	0.68
AFP-PseAAC	84.75	85.08	84.74	0.27	0.70
TargetFreeze
CryoProtect
Mean	87.39	73.84	87.69	0.29	0.61

Results were obtained from 1 round of random split.
Results were obtained from 3 rounds of random split.
Results were obtained from 20 rounds of random split.
Results reported from the work of TargetFreeze (He et al.).