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Journal of Chemistry
Volume 2018 (2018), Article ID 2785067, 6 pages
https://doi.org/10.1155/2018/2785067
Research Article

MCM-41-Accelerated PWA Catalysis of Friedel-Crafts Reaction of Indoles and Isatins

1Key Laboratory of Oil & Gas Fine Chemicals, Ministry of Education & Xinjiang Uyghur Autonomous Region, College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, China
2Department of Chemistry and Centre for Pharmacy, University of Bergen, 5020 Bergen, Norway

Correspondence should be addressed to YongHai Hui and Wei Wang

Received 22 July 2017; Accepted 1 November 2017; Published 18 January 2018

Academic Editor: Pasquale Longo

Copyright © 2018 Liuzhuang Xing et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Ordered mesoporous siliceous material has been identified as one of the key elements of the catalysis concept. Here we report an efficient Friedel-Crafts reaction of indoles with isatins catalyzed by PWA/MCM-41, which got the di(indolyl)indolin-2-ones derivatives with high yield. Moreover, the catalysts were characterized by XRD and SEM/EDS, the EDS spectrum indicated that the catalyst used in this reaction also contains tungsten, and the proposed mechanism for the synthesis of 3,3-di(indolyl)indolin-2-ones was also discussed. Finally, the catalyst can be reused repeatedly for several times without obvious loss of activity.