Transglycosylation Properties of a Novel <i>α</i>-1,4-Glucanotransferase from <i>Bacteroides thetaiotaomicron</i> and Its Application in Developing an <i>α</i>-Glucosidase-Specific Inhibitor

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Inhibitor</td><td class="align_center">Enzyme</td><td class="align_center">K<sub><i>i</i></sub> (<i>μ</i>M)</td><td class="align_center">Inhibition type</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left" rowspan="2">DNJ</td><td class="align_center"><i>α</i>-Glucosidase</td><td class="align_center">1.1</td><td class="align_center">Competitive</td></tr><tr><td class="align_center"><i>α</i>-Amylase</td><td class="align_center">4.4</td><td class="align_center">Competitive</td></tr><tr><td class="align_left" colspan="4"><hr/></td></tr><tr><td class="align_left" rowspan="2">G1-DNJ</td><td class="align_center"><i>α</i>-Glucosidase</td><td class="align_center">0.48</td><td class="align_center">Competitive</td></tr><tr><td class="align_center"><i>α</i>-Amylase</td><td class="align_center">—</td><td class="align_center">—</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Kinetic study of enzyme inhibition by DNJ and G1-DNJ.</div>

Journal of Chemistry

tab2

Table 2

Table 2: Transglycosylation Properties of a Novel <i>α</i>-1,4-Glucanotransferase from <i>Bacteroides thetaiotaomicron</i> and Its Application in Developing an <i>α</i>-Glucosidase-Specific Inhibitor 

Table 2 | Transglycosylation Properties of a Novel α-1,4-Glucanotransferase from Bacteroides thetaiotaomicron and Its Application in Developing an α-Glucosidase-Specific Inhibitor 