Research Article

L-Proline-Catalyzed Synthesis of Phthalimide Derivatives and Evaluation of Their Antioxidant, Anti-Inflammatory, and Lipoxygenase Inhibition Activities

Table 3

Lipoxygenase inhibition activity of compounds 17.

CompoundsLipoxygenase inhibition activity: IC50 (µM)

121.34 ± 0.72
265.21 ± 0.16
370.51 ± 0.65
420.45 ± 0.43
555.31 ± 0.31
657.53 ± 0.42
732.22 ± 0.16
Baicalein22.60