Research Article
Synthesis, Characterization, and Antibacterial and Anti-Inflammatory Activities of New Pyrimidine and Thiophene Derivatives
Table 2
The zones of inhibition (mm) of the synthesized compounds and standard antimicrobial drugs.
| | Compound number | Zone of inhibition (mm) | | Staphylococcus aureus | Bacillus | Escherichia coli | Klebsiella | Salmonella | Pseudomonas | Candida |
| | 3a | 11 ± 0.186 | — | — | — | — | — | — | | 3b | — | — | — | — | — | — | — | | 3c | — | — | — | — | — | — | — | | 3e | — | — | — | — | — | — | — | | 5b | — | — | — | — | — | — | — | | 5 | 16 ± 0.136 | 13 ± 0.501 | — | 12 ± 0.42 | 12 ± 0.075 | — | — | | 4b | — | — | — | — | — | 14 ± 0.056 | — | | 4c | — | — | — | — | — | 10 ± 0.138 | — | | 6a | 15 ± 0.322 | 15 ± 0.894 | — | — | — | — | — | | 6b | 10 ± 0.27 | — | — | — | — | — | — | | 6c | 13 ± 0.273 | 12 ± 0.071 | — | — | — | — | — | | Ampicillin | 30 ± 0.057 | 15 ± 0.069 | 25 ± 0.07 | 13 ± 0.062 | 34 ± 0.059 | 18 ± 0.054 | — | | Fluconazole | — | — | — | — | — | — | 38 ± 0.037 |
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