Evaluation of Novel N-(Dibenzylcarbamothioyl)benzamide Derivatives as Antibacterial Agents by Using DFT and Drug-Likeness Assessment

Table 2

Evaluation of Lipinski’s rule of five for compounds 2a, 2b, 2c, and 2d.

Lipinski rule/compounds	2a	2b	2c	2d
1. Log P (lipophilicity) < 5	5.8	6.6	5.8	5.8
2. Hydrogen bond donor < 5	1	1	1	1
3. Hydrogen bond acceptor < 10	2	2	2	2
4. Molecular weight < 500 g/mol	396.46	429.36	412.91	412.91