Table 3: % inhibition of compounds 5ae and 7ae against L. tropica leishmania.

CompoundCompound

5a0.65 ± 0.017a1.35 ± 0.04
5b0.68 ± 0.097b0.73 ± 0.12
5c0.81 ± 0.167c0.63 ± 0.18
5d0.68 ± 0.277d0.77 ± 0.08
5e0.89 ± 0.117e0.66 ± 0.18
Standard drug IC50(μg/mL ± SD)
Amphotericin B0.56 ± 0.20

inhibition activity: 100 = (nonsignificant; 0.95−0.80 = low; 0.79−0.70 = moderate; 0.69−0.60 = good; below 0.59−0.56 = significant activity).