Research Article

Crystal Structure and Biological Evaluation of Two Novel Organic-Inorganic Hybrid Materials as Antitumor Agents in the Treatment of Liver Cancer

Table 2

Antiproliferative activity IC50 (μM) of compounds 1 and 2.

CompoundsIC50 (μM)a
SMMC7721Bel-7402MHCC97

145.6 ± 2.149.2 ± 1.962.1 ± 1.2
250.3 ± 1.845.8 ± 2.159.5 ± 2.2
Doxorubicinb49.1 ± 2.050.1 ± 1.760.6 ± 2.1

aDrug concentration required to reduce cancer cell growth by 50%; bthe anticancer drug doxorubicin was chosen as the positive control.