Quantification of Mineral Oil Aromatic Hydrocarbons (MOAH) in Anhydrous Cosmetics Using ¹H NMR

Table 3

qNMR-analysis of pure mineral oil cosmetics and lipophilic cosmetics with further aromatic ingredients.

	Pure mineral oil cosmetics [3]	Lipophilic cosmetics with further aromatic ingredients
Cleanup step (SPE)	No	Yes. For lipstick/solid lip products, an additional preparation step to ensure homogeneity has to be carried out in advance.
Solvent	CDCl3/TMS^a	Cyclohexane
Temperature	55°C (bp CDCl3: 61°C)	75°C (bp cyclohexane: 81°C)
Sample solution for NMR	600 µL	480 µL diluted with 120 µL acetone-d6/TMS^a
Analytes	MOSH and MOAH	MOAH^b

^a0.1% tetramethylsilane. ^bMOSH signals are interfered by cyclohexane suppression.