Quantification of Mineral Oil Aromatic Hydrocarbons (MOAH) in Anhydrous Cosmetics Using ¹H NMR

Table 9

Breakthrough rates of aromatic ingredients frequently used in cosmetics with signals in the chemical shift region integrated for MOAH determination (δ 9.3–6.5 ppm) in ¹H NMR spectra.

INCI	Function in cosmetics	Breakthrough rate (%)^a
Benzyl benzoate	Antimicrobial, perfuming, solvent	0.2
BHA	Antioxidant, masking	0.0
BHT	Antioxidant, masking	90
Tocopherol	Antioxidant, masking, skin conditioning	0.5^b
Phenoxyethanol	Preservative	0.0
Methylparaben	Preservative	—^c
Ethylparaben	Preservative	—^c
Propylparaben	Preservative	—^c
Benzophenone-3	UV filter/absorber	0.0
Octocrylene	UV filter/absorber	0.0
Ethylhexyl methoxycinnamate	UV filter/absorber	0.0

^aDetermined by comparison of ¹H NMR results with and without SPE cleanup. ^bDetermined in a mixture of 70% tocopherol and 30% Helianthus annuus (sunflower) seed oil. ^cMainly insoluble in cyclohexane.