Extraction, Enrichment, and Quantification of Main Antioxidant Aglycones of Flavonoids and Tannins from Melastoma Dodecandrum Lour.: Guided by UPLC-ESI-MS/MS

Table 3

Box–Behnken design and result of response surface method analysis.

Run	Methanol concentration (X1) (%)	Extraction time (X2) (min)	Liquid-solid ratio (X3) (ml/mg)	Extraction yield (μmol TE/g)
1	75	30	0.4	2346.21 ± 225.54
2	100	30	0.3	1323.4 ± 181.8
3	50	30	0.5	2380.09 ± 28.83
4	75	30	0.4	2509.85 ± 72.34
5	75	45	0.3	2277.51 ± 155.14
6	100	45	0.4	1214.48 ± 211.17
7	100	30	0.5	1254.07 ± 96.16
8	75	30	0.4	2575.83 ± 113.58
9	75	45	0.5	2575.85 ± 110.16
10	75	15	0.3	2418.72 ± 15.54
11	75	30	0.4	2640.97 ± 429.23
12	50	45	0.4	2632.44 ± 128.83
13	100	15	0.4	1360.9 ± 144.1
14	50	30	0.3	2326.82 ± 55.19
15	75	30	0.4	2779.49 ± 291.99
16	50	15	0.4	2297.45 ± 225.81
17	75	15	0.5	2099.04 ± 89.07