Design and In Vitro Biological Evaluation of a Novel Organotin(IV) Complex with 1-(4-Carboxyphenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione

Figure 2

Fluorescent micrographs of acridine orange and ethidium bromide stained HeLa cells, untreated (a) or treated with [Ph₃Sn(CEMPD)] for 24 h (b) 2 × IC₅₀ and (c) 4 × IC₅₀. Arrows indicate apoptotic cells with condensed chromatin and/or fragmented nuclei while arrowheads mark necrotic cells.

(a)

(b)

(c)