Research Article

Design and In Vitro Biological Evaluation of a Novel Organotin(IV) Complex with 1-(4-Carboxyphenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione

Table 1

IC50 (µM) (mean ± SD) of CEMPDH, [Ph3Sn(CEMPD)], and cisplatin (72 h of action).

CompoundsIC50 (µM)
HeLaK562MDA-MB-453

CEMPDH>200>200>200
[Ph3Sn(CEMPD)]0.22 ± 0.040.53 ± 0.010.28 ± 0.03
Cisplatin6.90 ± 1.715.82 ± 0.176.73 ± 0.48