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Journal of Chemistry
/
2019
/
Article
/
Tab 1
/
Research Article
Design and
In Vitro
Biological Evaluation of a Novel Organotin(IV) Complex with 1-(4-Carboxyphenyl)-3-ethyl-3-methylpyrrolidine-2,5-dione
Table 1
IC
50
(
µ
M) (mean ± SD) of CEMPDH, [Ph
3
Sn(CEMPD)], and cisplatin (72 h of action).
Compounds
IC50 (
µ
M)
HeLa
K562
MDA-MB-453
CEMPDH
>200
>200
>200
[Ph
3
Sn(CEMPD)]
0.22 ± 0.04
0.53 ± 0.01
0.28 ± 0.03
Cisplatin
6.90 ± 1.71
5.82 ± 0.17
6.73 ± 0.48