Determination of the Lipophilicity of Ibuprofen, Naproxen, Ketoprofen, and Flurbiprofen with Thin-Layer Chromatography

Table 1

The chromatographic equations of the R_m = f(c) function for the analyzed compounds.

Compound	Equation
Isatin	Rm = −0.0214c + 0.8308
2,6-Dichloroaniline	Rm = −0.0274c + 2.0028
p-Nitrophenol	Rm = −0.0234c + 1.1115
3,4-Dichloroaniline	Rm = −0.0258c + 1.8251
N-(2,4-Dichlorophenyl)-acetamide	Rm = −0.0230c + 1.5421
N-(2,6-Dichlorophenyl)-acetamide	Rm = −0.0230c + 1.0612
Ketoprofen	Rm = −0.0306c + 1.8491
Naproxen	Rm = −0.0301c + 1.8623
Ibuprofen	Rm = −0.0319c + 2.3091
Flurbiprofen	Rm = −0.0366c + 2.5076