Design, Antileishmanial Activity, and QSAR Studies of a Series of Piplartine Analogues

Figure 3

Summary of the 3D-QSAR model. (a) Influence of the electrostatic properties of the compounds on bioactivity. (b) Influence of the steric factor on bioactivity. (c) Summary of the SAR derived from the 3D-QSAR analyses.

(a)

(b)

(c)