Review Article

Developments in Platinum-Group Metals as Dual Antibacterial and Anticancer Agents

Table 3

Cytostatic activities of Rh(III) coordination compounds and ed3a3 ligand against tumour strains in μM.

Compound IC50 (mM)MRC-5MCF-7A549HT-29HeLa

(1)>100>10016.831.961.10
(2)>100>10024.2837.6420.54
Na2Hed3a>100>10018.01>10013.86
Doxorubicin0.120.757.860.321.17
Cisplatin0.451.536.1222.052.02

(1) = [Rh(ed3a) (OH2)]·H2O; (2) = [Rh(ed3a) (OH2)]·H2O.