PI3K Inhibitors of Novel Hydrazide Analogues Linked 2-Pyridinyl Quinazolone Scaffold as Anticancer Agents

Figure 3

The suggested binding form of derivative 12 docked in the active position of PI3K showing (a) 2D and (b) 3D ligand-receptor interactions (H bonds are clarified as arrows; colored gray for C atoms, blue for N atoms, and red for O atoms).

(a)

(b)