PI3K Inhibitors of Novel Hydrazide Analogues Linked 2-Pyridinyl Quinazolone Scaffold as Anticancer Agents

Figure 4

The suggested binding form of derivative 16a docked in the active position of PI3K showing (a) 2D and (b) 3D ligand-receptor interactions, respectively (H bonds are clarified as arrows; C atoms are colored gray; N atoms are colored blue; O atoms are colored red).

(a)

(b)