Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P. aeruginosa Clinical Strains

Figure 1

Molecular structure of P. aeruginosa QS antagonists (#1, 2, 3, 4) designed on 3-O-C12-HSL scaffold. (a) LasR antagonist #1. (b) LasR antagonist #2. (c) LasR antagonist #3. (d) LasR antagonist #4.

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