Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P. aeruginosa Clinical Strains

Figure 8

Time-kill studies with PAO1 with concentration ranging from 0.5 to 8x the MIC of (a) ciprofloxacin or (b) ET37 treatment. Red arrow: “drug-tolerant” cells in ciprofloxacin-treated PAO1; blue arrow: “drug-tolerant” cells in ET37-treated PAO1.

(a)

(b)