Synthesis, DNA Binding, and Molecular Docking Studies of Dimethylaminobenzaldehyde-Based Bioactive Schiff Bases

Table 2

Antibacterial activity of heterocyclic Schiff base derivatives (1–8) along with experimental “log P” and the calculated “Clog P.”

Control	MIC (μg/mL)			Lipophilicity
	Staphylococcus aureus	Escherichia coli	Aspergillus niger	Log P	Clog P
1	200	200	200	3.40	3.23
2	150	200	150	2.67	2.98
3	125	150	125	4.42	4.26
4	50	75	50	3.83	4.02
5	50	50	75	3.84	4.08
6	125	150	150	4.52	4.33
7	125	125	125	2.96	3.17
8	50	75	75	3.93	4.09
Ofloxacin	11	13.5	—	—	—
Ketoconazole	—	—	13.5	—	—