Research Article

Pharmacokinetic Comparisons of Mangiferin and Mangiferin Monosodium Salt in Rat Plasma by UPLC-MS/MS

Table 1

Precision and accuracy of MG and MG-Na in rat plasma (x ± s ng/mL).

Plasma concentrationIntradayInterday
Mean concentrationRSD (%)RE (%)Mean concentrationRSD (%)RE (%)

MG
33.172 ± 0.1524.74.52.933 ± 0.1184.0−2.2
160166.357 ± 10.6746.43.9168.537 ± 11.7316.95.3
480486.523 ± 13.5432.91.4483.545 ± 23.8484.907

MG-Na
33.124 ± 0.1073.44.13.201 ± 0.1795.66.7
160168.343 ± 8.4725.05.2172.498 ± 10.5496.17.8
480491.573 ± 10.4562.12.4489.384 ± 16.3313.32.0