Research Article

Pharmacokinetic Comparisons of Mangiferin and Mangiferin Monosodium Salt in Rat Plasma by UPLC-MS/MS

Table 2

Extraction recovery and matrix effects of MG and MG-Na in rat plasma (x ± s ng/mL).

Plasma concentrationExtraction recovery rateMatrix effect
Recovery rate (%)RSD (%)RE (%)Matrix effect (%)RSD (%)RE (%)

MG
396.6 ± 4.24.2−3.497.1 ± 3.43.4−2.9
160103.5 ± 2.72.73.598.2 ± 2.32.3−1.8
48097.5 ± 3.33.3−2.598.5 ± 1.71.7−1.5

MG-Na
397.1 ± 2.82.8−2.998.3 ± 3.13.1−1.7
16098.6 ± 1.11.1−1.499.1 ± 1.31.3−0.9
480102.7 ± 2.32.3−2.798.2 ± 2.42.4−1.8