Research Article
Pharmacokinetic Comparisons of Mangiferin and Mangiferin Monosodium Salt in Rat Plasma by UPLC-MS/MS
Table 5
Mean compartmental pharmacokinetic parameters of MG and MG-Na (x ± s).
| | | Tmax (min) | Cmax (μg/L) | t1/2 (min) | | | K10 (1/min) | Ka (1/min) | CL/F (L/min/kg) | V1/F (L/kg) | F (%) |
| | MG | 60.00 ± 0.00 | 23.878 ± 4.457 | 69.315 ± 11.782 | 7565.692 ± 1731.293 | 7600.169 ± 1687.238 | 0.002 ± 0.000 | 0.022 ± 0.001 | 13.158 ± 1.589 | 2693.381 ± 355.336 | 100 | | MG-Na | 15.00 ± 0.00 | 496.867 ± 79.472 | 72.315 ± 10.652 | 42493.728 ± 580.387 | 42983.947 ± 674.291 | 0.009 ± 0.001 | 1.84 ± 0.129 | 2.326 ± 0.448 | 248.442 ± 20.351 | 570 |
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indicates significant differences from the MG. indicates highly significant differences from the MG. |
